陈志俊论文成果

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陈志俊Zhijun Chen

(教授)

学位：博士
性别：男
学历：博士研究生毕业
在职信息：在职
所在单位：化学学院

论文成果

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Chen Z, Pudas R, Sharma S, Smart O, Juffer A, Hiltunen JK, Wierenga RK,Haapalainen AM. Structure and enzymology of 2-enoyl thioester reductase of human FAS II: New insights into substrate binding and catalysis. J. Mol. Biol. 379:830–844, 2008.
Chen Z, Leskinen H, Liimatta E, Sormunen RT, Miinalainen IJ, Hassinen IE, Hiltunen JK. Overexpression of 2-enoyl thioester reducatse of mitochondrial FASII in heart leads to cardiac dysfunction in mouse. PLoS ONE 4:e5589, 2009.
Chen Z, Kastaniotis AJ, Miinalainen IJ, Rajaram V, Wierenga RK, Hiltunen JK. 17β-Hydroxysteroid dehydrogenase type 8 and carbonyl reductase type 4 assemble as a ketoacyl reductase of human mitochondrial FAS. FASEB J. 23:3682-91, 2009.
Hiltunen JK, Chen Z, Haapalainen AM, Wierenga RK and Kastaniotis AJ. Mitochondrial fatty acid synthesis - an adopted set of enzymes making a pathway of major importance for the cellular metabolism. Prog. in Lipid Res. 49:27-45, 2010.
Ma Y, Zhou M, Walter S, Liang J, Chen Z*, Wu L*. Selective adhesion and controlled activity of yeast cells on honeycomb-patterned polymer films via a microemulsion approach. Chem. Commun. 2014, 50: 15882-85.
Ding H, Liang C, Sun K, Wang H, Hiltunen JK, Chen Z*, Shen J. Dithiothreitol-capped fluorescent gold nanoclusters: An efficient probe for detection of copper(II) ions in aqueous solution. Biosens. Bioelectron. 2014, 59: 216–20.
Venkatesan R*, Sah-Teli SK, Awoniyi LO, Jiang G, Prus P, Kastaniotis AJ, Hiltunen JK, Wierenga RK, Chen Z*. Insights into mitochondrial fatty acid synthesis from the structure of heterotetrameric 3-ketoacyl-ACP reductase/3R-hydroxyacyl-CoA dehydrogenase. Nat. Comm. 2014, 5: 4805, 1-12.
Ding H, Yang D, Zhao C, Song Z, Liu P, Wang Y, Chen Z*, Shen J. Protein–gold hybrid nanocubes for cell imaging and drug delivery. ACS Appl. Mater. Interfaces 2015, 7, 4713-4719.
Ding H, Du F, Liu P, Chen Z*, Shen J. DNA–carbon dots function as fluorescent vehicles for drug delivery. ACS Appl. Mater. Interfaces 2015, 7, 6889-6897.
Liu P, Wang X, Hiltunen K, Chen Z*. Controllable drug release system in living cells triggered by enzyme-substrate recognition. ACS Appl. Mater. Interfaces 2015, 7, 26811−26818.
Wang X, Zhang J, Wang Y, Liu Y, Li Z, Xie Z*, Chen Z*. Fluorescent protein nanovessels: a new platform to generate bio-abiotic hybrid materials for bioimaging, Adv. Funct. Mater. 2017, 1702051, 1-8.
Ding H*, Li H, Wang X, Zhou Y, Li Z, Hiltunen JK, Shen J, Chen Z*. Expanding toolbox of imagable protein-Gold hybrid materials. Chem. Mater. 2017, 29 (19), pp 8440–8448
Zhenhua Li, Han Ding, Fei Yan, Hongwei * and Zhijun Chen* .Transformable protein–gold hybrid materials serve as supramolecular vehicles for gene delivery. RSC Adv., 2017, 7, 51252-51256
Zhenhua Li, Xiaoliang Wang, Zhuo Tian* and Zhijun Chen* .Fluorescent protein nanovessels packing DNA into a nucleosome-like gene carrier.New J. Chem., 2018,42, 2776-2781
Xiaoliang Wang, Yang Liu, Jiao Liu,Zhijun Chen* .Protein‐Polymer Microcapsule for PCR Technology. Chembiochem. https://doi.org/10.1002/cbic.201800080

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基本信息

陈志俊Zhijun Chen

论文成果

Chen Z, Pudas R, Sharma S, Smart O, Juffer A, Hiltunen JK, Wierenga RK,Haapalainen AM. Structure and enzymology of 2-enoyl thioester reductase of human FAS II: New insights into substrate binding and catalysis. J. Mol. Biol. 379:830–844, 2008.

Chen Z, Leskinen H, Liimatta E, Sormunen RT, Miinalainen IJ, Hassinen IE, Hiltunen JK. Overexpression of 2-enoyl thioester reducatse of mitochondrial FASII in heart leads to cardiac dysfunction in mouse. PLoS ONE 4:e5589, 2009.

Chen Z, Kastaniotis AJ, Miinalainen IJ, Rajaram V, Wierenga RK, Hiltunen JK. 17β-Hydroxysteroid dehydrogenase type 8 and carbonyl reductase type 4 assemble as a ketoacyl reductase of human mitochondrial FAS. FASEB J. 23:3682-91, 2009.

Hiltunen JK, Chen Z, Haapalainen AM, Wierenga RK and Kastaniotis AJ. Mitochondrial fatty acid synthesis - an adopted set of enzymes making a pathway of major importance for the cellular metabolism. Prog. in Lipid Res. 49:27-45, 2010.

Ma Y, Zhou M, Walter S, Liang J, Chen Z, Wu L. Selective adhesion and controlled activity of yeast cells on honeycomb-patterned polymer films via a microemulsion approach. Chem. Commun. 2014, 50: 15882-85.

Ding H, Liang C, Sun K, Wang H, Hiltunen JK, Chen Z*, Shen J. Dithiothreitol-capped fluorescent gold nanoclusters: An efficient probe for detection of copper(II) ions in aqueous solution. Biosens. Bioelectron. 2014, 59: 216–20.

Venkatesan R, Sah-Teli SK, Awoniyi LO, Jiang G, Prus P, Kastaniotis AJ, Hiltunen JK, Wierenga RK, Chen Z. Insights into mitochondrial fatty acid synthesis from the structure of heterotetrameric 3-ketoacyl-ACP reductase/3R-hydroxyacyl-CoA dehydrogenase. Nat. Comm. 2014, 5: 4805, 1-12.

Ding H, Yang D, Zhao C, Song Z, Liu P, Wang Y, Chen Z*, Shen J. Protein–gold hybrid nanocubes for cell imaging and drug delivery. ACS Appl. Mater. Interfaces 2015, 7, 4713-4719.

Ding H, Du F, Liu P, Chen Z*, Shen J. DNA–carbon dots function as fluorescent vehicles for drug delivery. ACS Appl. Mater. Interfaces 2015, 7, 6889-6897.

Liu P, Wang X, Hiltunen K, Chen Z*. Controllable drug release system in living cells triggered by enzyme-substrate recognition. ACS Appl. Mater. Interfaces 2015, 7, 26811−26818.

Wang X, Zhang J, Wang Y, Liu Y, Li Z, Xie Z, Chen Z. Fluorescent protein nanovessels: a new platform to generate bio-abiotic hybrid materials for bioimaging, Adv. Funct. Mater. 2017, 1702051, 1-8.

Ding H, Li H, Wang X, Zhou Y, Li Z, Hiltunen JK, Shen J, Chen Z. Expanding toolbox of imagable protein-Gold hybrid materials. Chem. Mater. 2017, 29 (19), pp 8440–8448

Zhenhua Li, Han Ding, Fei Yan, Hongwei * and Zhijun Chen* .Transformable protein–gold hybrid materials serve as supramolecular vehicles for gene delivery. RSC Adv., 2017, 7, 51252-51256

Zhenhua Li, Xiaoliang Wang, Zhuo Tian* and Zhijun Chen* .Fluorescent protein nanovessels packing DNA into a nucleosome-like gene carrier.New J. Chem., 2018,42, 2776-2781

Xiaoliang Wang, Yang Liu, Jiao Liu,Zhijun Chen* .Protein‐Polymer Microcapsule for PCR Technology. Chembiochem. https://doi.org/10.1002/cbic.201800080

基本信息

陈志俊Zhijun Chen

论文成果

Chen Z, Pudas R, Sharma S, Smart O, Juffer A, Hiltunen JK, Wierenga RK,Haapalainen AM. Structure and enzymology of 2-enoyl thioester reductase of human FAS II: New insights into substrate binding and catalysis. J. Mol. Biol. 379:830–844, 2008.

Chen Z, Leskinen H, Liimatta E, Sormunen RT, Miinalainen IJ, Hassinen IE, Hiltunen JK. Overexpression of 2-enoyl thioester reducatse of mitochondrial FASII in heart leads to cardiac dysfunction in mouse. PLoS ONE 4:e5589, 2009.

Chen Z, Kastaniotis AJ, Miinalainen IJ, Rajaram V, Wierenga RK, Hiltunen JK. 17β-Hydroxysteroid dehydrogenase type 8 and carbonyl reductase type 4 assemble as a ketoacyl reductase of human mitochondrial FAS. FASEB J. 23:3682-91, 2009.

Hiltunen JK, Chen Z, Haapalainen AM, Wierenga RK and Kastaniotis AJ. Mitochondrial fatty acid synthesis - an adopted set of enzymes making a pathway of major importance for the cellular metabolism. Prog. in Lipid Res. 49:27-45, 2010.

Ma Y, Zhou M, Walter S, Liang J, Chen Z*, Wu L*. Selective adhesion and controlled activity of yeast cells on honeycomb-patterned polymer films via a microemulsion approach. Chem. Commun. 2014, 50: 15882-85.

Ding H, Liang C, Sun K, Wang H, Hiltunen JK, Chen Z*, Shen J. Dithiothreitol-capped fluorescent gold nanoclusters: An efficient probe for detection of copper(II) ions in aqueous solution. Biosens. Bioelectron. 2014, 59: 216–20.

Venkatesan R*, Sah-Teli SK, Awoniyi LO, Jiang G, Prus P, Kastaniotis AJ, Hiltunen JK, Wierenga RK, Chen Z*. Insights into mitochondrial fatty acid synthesis from the structure of heterotetrameric 3-ketoacyl-ACP reductase/3R-hydroxyacyl-CoA dehydrogenase. Nat. Comm. 2014, 5: 4805, 1-12.

Ding H, Yang D, Zhao C, Song Z, Liu P, Wang Y, Chen Z*, Shen J. Protein–gold hybrid nanocubes for cell imaging and drug delivery. ACS Appl. Mater. Interfaces 2015, 7, 4713-4719.

Ding H, Du F, Liu P, Chen Z*, Shen J. DNA–carbon dots function as fluorescent vehicles for drug delivery. ACS Appl. Mater. Interfaces 2015, 7, 6889-6897.

Liu P, Wang X, Hiltunen K, Chen Z*. Controllable drug release system in living cells triggered by enzyme-substrate recognition. ACS Appl. Mater. Interfaces 2015, 7, 26811−26818.

Wang X, Zhang J, Wang Y, Liu Y, Li Z, Xie Z*, Chen Z*. Fluorescent protein nanovessels: a new platform to generate bio-abiotic hybrid materials for bioimaging, Adv. Funct. Mater. 2017, 1702051, 1-8.

Ding H*, Li H, Wang X, Zhou Y, Li Z, Hiltunen JK, Shen J, Chen Z*. Expanding toolbox of imagable protein-Gold hybrid materials. Chem. Mater. 2017, 29 (19), pp 8440–8448

Zhenhua Li, Han Ding, Fei Yan, Hongwei * and Zhijun Chen* .Transformable protein–gold hybrid materials serve as supramolecular vehicles for gene delivery. RSC Adv., 2017, 7, 51252-51256

Zhenhua Li, Xiaoliang Wang, Zhuo Tian* and Zhijun Chen* .Fluorescent protein nanovessels packing DNA into a nucleosome-like gene carrier.New J. Chem., 2018,42, 2776-2781

Xiaoliang Wang, Yang Liu, Jiao Liu,Zhijun Chen* .Protein‐Polymer Microcapsule for PCR Technology. Chembiochem. https://doi.org/10.1002/cbic.201800080

Ma Y, Zhou M, Walter S, Liang J, Chen Z, Wu L. Selective adhesion and controlled activity of yeast cells on honeycomb-patterned polymer films via a microemulsion approach. Chem. Commun. 2014, 50: 15882-85.

Venkatesan R, Sah-Teli SK, Awoniyi LO, Jiang G, Prus P, Kastaniotis AJ, Hiltunen JK, Wierenga RK, Chen Z. Insights into mitochondrial fatty acid synthesis from the structure of heterotetrameric 3-ketoacyl-ACP reductase/3R-hydroxyacyl-CoA dehydrogenase. Nat. Comm. 2014, 5: 4805, 1-12.

Wang X, Zhang J, Wang Y, Liu Y, Li Z, Xie Z, Chen Z. Fluorescent protein nanovessels: a new platform to generate bio-abiotic hybrid materials for bioimaging, Adv. Funct. Mater. 2017, 1702051, 1-8.

Ding H, Li H, Wang X, Zhou Y, Li Z, Hiltunen JK, Shen J, Chen Z. Expanding toolbox of imagable protein-Gold hybrid materials. Chem. Mater. 2017, 29 (19), pp 8440–8448