吴玉清 Scientific Research

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国家自然科学基金委面上项目青年基金，20003004，含硒抗体酶活性部位结构及作用机理的光谱学研究，2001/01-2003/12, 17万元，已结题，主持。

国家自然科学基金委面上项目，20373017，手性修饰生物功能分子与蛋白质分子识别相互作用的光谱学研究，2004/01-2006/12，25万元，已结题，主持。

国家自然科学基金委面上项目，20473028，双变量诱导溶液中蛋白质构象变化的混合二维相关光谱研究，2005/01-2007/12，23万元, 已结题，主持

国家重点基础研究发展计划（973）课题, 2007CB808006，分子聚集体的化学—分子自组装与组装体的功能，2007/5-2012/5，50万元，参加。

教育部新世纪优秀人才支持计划，NCET-06-0310，若干生物体系分子识别及相关机理的谱学研究，2007/01-2009/12，25万元, 已结题，主持。

吉林省科技发展计划项目，20070926-01，组织蛋白酶天然药物抑制剂的研究与开发2007/01-2009/12， 8万元, 已结题，主持。

“肼腈类组织蛋白酶K抑制剂及其在治疗骨关节炎药物中的应用” 发明专利，申请号或专利号：ZL201610207293.X；专利权人:吉林大学.申请人：吴玉清，原晓喻，瑞尼-布希，萨伊达-穆拜瑞柯.

“一类以三氟乙氨基为P2-P3连接基团的肼腈类组织蛋白酶抑制剂及应用”，发明专利，申请号或专利号：201510366741.6；

人乳头瘤病毒L1蛋白突变体及其制备方法发明专利，申请号或专利号：ZL 201310688551.7；

一种抑制HPV L1五聚体形成的抑制剂，发明专利，申请号或专利号：ZL 201310690014.6；申请人：吴玉清，潘东，金石，付丁伊，刘永江，陈小江. 申请日均为2013.12.17

“肼腈类组织蛋白酶K抑制剂及其在治疗骨质疏松症方面的应用” 发明专利，申请号或专利号：ZL 2013 1 0021388.9；专利权人:吉林大学.申请人：吴玉清，原晓喻.

“具有不同P3位结构的肼腈类组织蛋白酶抑制剂及应用”，发明专利，申请号或专利号：ZL 2012 1 0179098.2；专利权人:吉林大学，申请人：吴玉清，任兴凤，李洪伟

Paper Publication... More>>

X. Yu, C.-X. Zhang, L. Zhang, Y.-R. Xue, H.-W. Li, Y. Wu, The construction of a FRET assembly by using gold nanoclusters and carbon dots and their application as a ratiometric probe for cysteine detection, Sensors and Actuators B: Chemical, 263(2018) 327-35.

“Cell receptor screening for human papillomavirus invasion by using a polyoxometalate-peptide assembly as a probe” Peng-Fan Gao, Yuxue Liu, Lening Zhang, Hong-Wei Li*, Yuqing Wu*, Lixin Wu J. Colloid Interface Sci. 2018, 514, 407–414.

“Disperse magnetic solid phase microextraction and surface enhanced Raman scattering (Dis-MSPME-SERS) for the rapid detection of trace illegally chemicals.” Shihua Yu, Zhigang Liu, Weixian Wang, Li Jin, Weiqing Xu, Yuqing Wu,* Talanta 2018, 178498-178506.

“Combination of a graphene SERS substrate and magnetic solid phase micro-extraction used for the rapid detection of trace illegal additives” Shihua Yu, Zhigang Liu, Hongwei Li, Jianpo Zhang, Xin-xin Yuan, Xiangyu Jia, Yuqing Wu* The Analyst 2018, 143 (4 ), 883-890.

“Hybrid Assembly toward EnhancedThermal Stability of Virus-likeParticles and AntibacterialActivity of Polyoxometalates” Ding-Yi Fu, Simin Zhang, Yuqing Wu* and Lixin Wu* ACS Appl Mater Interfaces 2018 Feb; 10 (7): 6137-6145.

“Hydrothermal synthesis of novel photosensitive gold and silver bimetallic nanoclusters protected by adenosine monophosphate (amp)” Jiao Liu, Xin-Xin Yuan, Hong-Wei Li,* Yuqing Wu J. Mater. Chem. C, 2017, 5, 9979-9985.

Design and synthesis of high specific fluorescent sensors

Molecular recognition, assembly and functions in Biology system

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Alma Mater : Jilin University

Education Level : 博士研究生毕业

Degree : 博士

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Discipline : 物理化学

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